| Document ID (ISN) | 107053 |
| CIS number |
07-1205 |
| ISSN - Serial title |
0340-0131 - International Archives of Occupational and Environmental Health |
| Year |
2006 |
| Convention or series no. |
|
| Author(s) |
Müller T., Jörres R.A., Scharrer E.M., Hessel H., Nowak D., Radon K. |
| Title |
Acute blood neutrophilia induced by short-term compost dust exposure in previously unexposed healthy individuals |
| Bibliographic information |
June 2006, Vol.79, No.6, p.477-482. 36 ref. |
| Abstract |
The purpose of this study was to examine whether a single exposure at a composting facility could exert systemic effects in healthy volunteers not previously exposed to organic dust from such facilities. Seventeen subjects (aged 20-35 years) were exposed to organic dust for 2h (exposure day) during moderate exercise; 12 of these subjects also took part in a control experiment (control day), without exposure. Spirometry was performed before and immediately after the exposure. White blood cell counts and levels of tumour-necrosis factor-α, interleukin-1β and interleukin-6 in peripheral blood were determined before and 3h after exposure. Short-term exposure of healthy, young subjects to organic dust from composting facilities had opposite effects on the numbers of blood neutrophils and blood eosinophils. These effects, though mild, suggest that even a limited period of moderate work may cause a sufficient amount of bioactive material to be deposited in the lung to elicit acute systemic alterations. |
| Descriptors (primary) |
compost; biological hazards; organic dust |
| Descriptors (secondary) |
blood count; pulmonary function; neutrophil changes; interleukins |
| Document type |
D - Periodical articles |
| Country / State or Province | Germany |
| Subject(s) |
Dust, aerosols and related diseases
|
| Broad subject area(s) |
Biological hazards
|
| Browse category(ies) |
Biological hazards
|
