|Document ID (ISN)||106935|
|ISSN - Serial title
||0340-0131 - International Archives of Occupational and Environmental Health
|Convention or series no.
||Wu M.T., et al.
||Sperm DNA damage correlates with polycyclic aromatic hydrocarbons biomarker in coke-oven workers
||May 2006, Vol.79, No.5, p.349-356. Illus. 41 ref.
||http://www.springerlink.com/content/fx70q8u68g494803/fulltext.pdf [in English]
||The aim of this study was to determine whether occupational exposure to polycyclic aromatic hydrocarbons (PAHs) in men has an adverse effect on semen quality. Forty-eight coke-oven workers, including 16 topside-oven workers and 32 side-oven workers, were studied. Ambient PAHs exposure, urinary 1-hydroxypyrene (1-OHP) levels and parameters of semen quality were determined. Findings are discussed. A potential risk of sperm dysfunction should be considered for workers occupationally exposed to high levels of PAHs. Cigarette smoking may aggravate this risk. Urinary 1-OHP was found to be a useful a biomarker for predicting sperm dysfunction.
||aromatic hydrocarbons; polycyclic hydrocarbons; spermatogenic disturbances; coke ovens
||Taiwan (China); DNA; smoking; determination in urine; genetic effects; determination in air; 1-hydroxypyrene
||D - Periodical articles
|Country / State or Province||Taiwan (China)|
||Metal production and metalworking
|Broad subject area(s)
||Diseases of the reproductive system
Genetic factors in reaction to exposures