|Document ID (ISN)||106739|
|ISSN - Serial title
||0105-1873 - Contact Dermatitis
|Convention or series no.
||Madan V., Beck M.H.
||Occupational allergic contact dermatitis from N,N-methylene-bis-5-methyl-oxazolidine in coolant oils
||July 2006, Vol.55, No.1, p.39-41. 10 ref.
||Contact with metal working fluids (MWF) is an important factor in the development of occupational hand dermatitis in patients working in the metal processing industry. Biocides are added to MWF as preservatives and are known sensitizers. This study analysed 318 patch test reactions to N,N-methylene-bis-5-methyl-oxazolidine 1% in petrolatum present in coolant oils in patients exposed to MWF and with suspected occupational dermatitis. Positive allergic reactions were noted in 15 cases. In seven cases, it was possible to confirm the presence of N,N-methylene-bis-5-methyl-oxazolidine in the oils used by the patients. Positive reactions to formaldehyde were seen in 11 patients. Sensitization to N,N-methylene-bis-5-methyl-oxazolidine and/or formaldehyde allergy was considered likely to have contributed to the workers' dermatitis.
||allergens; 3,3'-methylene-bis(5-methyloxazolidine); metalworking industry; skin diseases; cutting fluids; biocides
||formaldehyde; sensitization; skin tests; eczema
||D - Periodical articles
|Country / State or Province||United Kingdom|
||Toxic and dangerous substances
|Broad subject area(s)