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Document ID (ISN)106466
CIS number 07-327
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2006
Convention or series no.
Author(s) Magnusson L.L., Bodin L., Wennborg H.
Title Adverse pregnancy outcomes in offspring of fathers working in biomedical research laboratories
Bibliographic information 2006, Vol.49, p.468-473. Illus. 28 ref.
Abstract Laboratory work may constitute a possible health hazard for workers as well as for their offspring, and involves a wide range of exposures, such as organic solvents, carcinogenic agents, ionizing radiation and microorganisms. This study examined adverse pregnancy outcomes in the offspring of male employees of biomedical research laboratories. Pregnancy parameters of offspring to male workers employed between 1970 and 1989 at four Swedish universities were identified from birth registers. Offspring of 2281 fathers with laboratory work were considered exposed, and of 1909 non-laboratory employees unexposed. Exposure data were obtained by questionnaire. Logistic regression analysis estimated odds ratios and confidence intervals. There was no clear association between periconceptional paternal laboratory work and adverse reproductive outcomes, but use of radioactive isotopes showed increased risk of high birth weight in offspring.
Descriptors (primary) male workers; complications of pregnancy; laboratory work; parental exposure
Descriptors (secondary) ionizing radiation; carcinogens; case-control study; organic solvents; questionnaire survey; Sweden
Document type D - Periodical articles
Country / State or ProvinceSweden
Subject(s) Commerce, services, offices
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Diseases of the reproductive system