Document ID (ISN) | 106398 |
CIS number |
07-397 |
ISSN - Serial title |
0340-0131 - International Archives of Occupational and Environmental Health |
Year |
2006 |
Convention or series no. |
|
Author(s) |
van Thriel C., et al. |
Title |
From chemosensory thresholds to whole-body exposures - Experimental approaches for evaluating chemosensory effects of chemicals |
Bibliographic information |
Apr. 2006, Vol.79, No.4, p.308-321. Illus. 44 ref. |
Abstract |
The avoidance of adverse chemosensory effects is essential at workplaces where volatile chemicals are used. In the first part of this study, the odour (OT) and irritation thresholds (IT) of 15 irritants were determined in a random sample of 144 persons stratified for gender and age. Irritants exhibiting high chemosensory potency were selected for the second psychophysical part of the study, where 48 persons, again stratified for gender and age, rated the intensity of 13 trigeminal and olfactory perceptions elicited by nine ascending concentrations of the irritants. Across the investigated chemicals, the transition from concentrations eliciting pure olfactory stimulation (OT) to trigeminal stimulation (IT) differed markedly. Gender and age had only weak impact on the chemosensory thresholds. |
Descriptors (primary) |
irritation; volatile substances; olfactometry; olfaction; chemical products |
Descriptors (secondary) |
subjective assessment; odour threshold; individual susceptibility; evaluation of technique; exposure evaluation |
Document type |
D - Periodical articles |
Country / State or Province | Germany |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
Chemical safety
|
Browse category(ies) |
Diseases of other sense organs (other than the eye and the ears)
|