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Document ID (ISN)106362
CIS number 07-386
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 2006
Convention or series no.
Author(s) Lidén C., Skare L., Lind B., Nise G., Vahter M.
Title Assessment of skin exposure to nickel, chromium and cobalt by acid wipe sampling and ICP-MS
Bibliographic information May 2006, Vol.54, No.5, p.233-238. Illus. 17 ref.
Abstract This article describes a technique developed for the assessment of skin exposure to nickel, chromium and cobalt based on sampling with cellulose wipes impregnated with 1% nitric acid. Chemical analysis was performed by inductively coupled plasma mass spectrometry (ICP-MS). The recovery of nickel, chromium and cobalt from arms and palms was 93%. The analytical result is expressed in terms of mass per unit area (µg/cm2). The developed acid wipe sampling technique was found to be suitable for determination of nickel, chromium and cobalt deposited on the skin. The technique may be used in workplace studies, in studies of individuals in the general population, in dermatitis patients, in identification of risk groups, as well as in developing preventive strategies and in follow-up after intervention.
Descriptors (primary) cobalt; nickel; chromium; exposure evaluation; skin absorption
Descriptors (secondary) mass spectrometry; plasma emission spectrometry; description of technique; sampling and analysis
Document type D - Periodical articles
Country / State or ProvinceSweden
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Exposure evaluation
Nickel and compounds
Inorganic substances