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CISDOC database

Document ID (ISN)106063
CIS number 07-198
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2006
Convention or series no.
Author(s) M÷hner M., Lindtner M., Otten H., Gille H.G.
Title Leukemia and exposure to ionizing radiation among German uranium miners
Bibliographic information Apr. 2006, Vol.49, No.4, p.238-248. Illus. 23 ref.
Abstract It is well known that uranium miners are at an increased risk of lung cancer. Whether they also have an increased risk for other cancer sites remains under discussion. The aim of this study was to examine the leukaemia risk among uranium miners. It involved 377 former uranium miners in East Germany and 980 matched controls. Using conditional logistic regression models, a dose-response relationship between leukaemia risk and exposure to radon progeny could not be confirmed. Yet, a significantly elevated risk is seen in workers with the highest exposure to the combined effect of γ-radiation and long-lived radionuclides. The results suggest that an elevated risk for leukaemia is restricted to employees with a very long occupational career in underground uranium mining or uranium processing. Moreover, the study does not support the hypothesis of an association between exposure to short-lived radon progeny and leukaemia risk.
Descriptors (primary) leukaemia; uranium mining; radon; Germany
Descriptors (secondary) ionizing radiation; case-control study; exposure evaluation; radon daughters
Document type D - Periodical articles
Country / State or ProvinceGermany
Subject(s) Mines and quarries
Broad subject area(s) Physical hazards
Occupational medicine, epidemiology
Browse category(ies) Inorganic substances
Radon
Leukaemia
Mining and quarrying