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Document ID (ISN)105492
CIS number 06-907
ISSN - Serial title 1077-3525 - International Journal of Occupational and Environmental Health
Year 2006
Convention or series no.
Author(s) Huh J.W., Hong S.B., Lim C.M., Do K.H., Lee J.S., Koh Y.S.
Title Sequential radiologic and functional pulmonary changes in patients with paraquat intoxication
Bibliographic information July-Sep. 2006, Vol.12, No.3, p.203-208. Illus. 24 ref.
Internet access http://www.ijoeh.com/pfds/IJOEH_1203_Huh.pdf [in English]
Abstract The sequential changes of paraquat-induced pulmonary damage were studied using high-resolution computed tomography (HRCT) and pulmonary function tests (PFTs) in long-term follow-up. Among the cohort of 27 patients who had ingested paraquat, the HRCT findings showed a normal (n=14) and an abnormal group (n=13). Increased paraquat ingestion in the abnormal group was associated with more rapid and severe pulmonary changes. Ground-glass opacity on HRCT peaked on day 7 after ingestion. Between 2 weeks and 1 month, consolidation increased and pulmonary fibrosis progressed, and slow improvements were observed for up to six months. Compared with the PFT results obtained at 1 and 6.5 months, FVC, FEV1, and diffusing capacity all improved slightly. Lung changes after paraquat intoxication are functionally and radiologically reversible following treatment. [Abstract supplied by the journal]
Descriptors (primary) poisoning; radiological changes; pulmonary function; paraquat
Descriptors (secondary) ingestion; tomography; pulmonary fibrosis
Document type D - Periodical articles
Country / State or ProvinceKorea, Republic of
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Heterocyclic compounds