ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)105389
CIS number 06-898
ISSN - Serial title 1231-868X - Podstawy i Metody Oceny Środowiska Pracy
Year 2005
Convention or series no.
Author(s) Gołofit-Szymczak M.
Title 4,4'-Methylenedianiline: Documentation of maximum admissible values for occupational exposure
Original title 4,4'-Metylenodianilina: Dokumentacja proponowanych wartości dopuszczalnych wielkości narażenia zawodowego [in Polish]
Bibliographic information 2005, Vol.44, No.2, p.131-161. 78 ref.
Abstract 4,4'-Methylenodianiline (MDA) exists as colourless to pale yellow crystalline flakes. Occupational exposure to MDA occurs by dermal, oral and inhalation routes. MDA is a hepatotoxic agent. Acute human exposure to MDA results in liver damage, cholangitis and centrilobular cholestasis. Chronic exposure also causes liver damage. The Expert Group has recommended a TLV of 0.8 mg/m3 for 4,4' -methylenodianiline. A skin notation and a carcinogen notation (probably carcinogenic to humans) are also assigned.
Descriptors (primary) toxic effects; methylenedianiline; carcinogens; threshold limit values
Descriptors (secondary) hepatic damage; carcinogenic effects; skin absorption
Document type D - Periodical articles
Country / State or ProvincePoland
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Aromatic amines
Occupational exposure limits