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Document ID (ISN)105056
CIS number 06-631
ISSN - Serial title 0340-0131 - International Archives of Occupational and Environmental Health
Year 2005
Convention or series no.
Author(s) Fransman W., Vermeulen R., Kromhout H.
Title Dermal exposure to cyclophosphamide in hospitals during preparation, nursing and cleaning activities
Bibliographic information June 2005, Vol.78, No.5, p.403-412. Illus. 23 ref.
Internet access http://www.springerlink.com/media/9e2751k1pl5xnh48bx4g/contributions/q/2/0/6/q2065842242510v7.pdf [in English]
Abstract This study investigated potential and actual levels of dermal exposure to cyclophosphamide (CP) used in oncology treatment in hospitals. Exposure was assessed during various tasks by the collection of samples from protective gloves and protective clothing and from hand, forearm and forehead skin. Results demonstrated that actual dermal exposure to CP is common among oncology nurses working with patients treated with this drug. Pharmacy technicians and cleaning personnel, on the other hand, are only potentially exposed to CP, and protection provided by gloves appears to be sufficient.
Descriptors (primary) antineoplastic drugs; cyclophosphamide; health care personnel; hospitals; skin absorption
Descriptors (secondary) protective gloves; domestic and related helpers, cleaners; exposure evaluation; hazard evaluation
Document type D - Periodical articles
Country / State or ProvinceNetherlands
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Health care services
Heterocyclic compounds
Domestic workers