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Document ID (ISN)104856
CIS number 06-368
ISSN - Serial title 0340-0131 - International Archives of Occupational and Environmental Health
Year 2005
Convention or series no.
Author(s) Uitti J., Nordman H., Halmepuro L., Savolainen J.
Title IgG4 response to fur animal allergens among fur workers
Bibliographic information Feb. 2005, Vol.78, No.1, p.71-74. 18 ref.
Abstract The aim of this study was to determine whether IgG4 antibodies to allergens in urine extracts from fur animals were associated with positive prick tests to the same allergens and with the occurrence of respiratory symptoms among fur workers. IgG4 antibodies to mink and silver fox urine were analysed in fur farmers and three referent groups from the plastics industry. The fur workers had higher IgG4 values than other groups and also had urinary IgG4 antibodies more frequently than the other groups. Among the exposed subjects, IgG4 antibodies correlated with positive skin prick tests to the same allergens and were associated with symptoms among the exposed workers. Results indicate that IgG4 antibodies are a good indicator of exposure to these allergens in fur workers.
Descriptors (primary) allergens; fur industry; handling of animals; immunology
Descriptors (secondary) rhinitis; eye irritation; antibodies; frequency rates; case-control study; skin tests; symptoms
Document type D - Periodical articles
Country / State or ProvinceFinland
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Footwear, leather and fur industry
Livestock rearing