| Document ID (ISN) | 104648 |
| CIS number |
06-129 |
| ISSN - Serial title |
1231-868X - Podstawy i Metody Oceny Środowiska Pracy |
| Year |
2005 |
| Convention or series no. |
|
| Author(s) |
Starek A. |
| Title |
1,1-Dichloro-l-nitroethane: Documentation of maximum admissible values for occupational exposure |
| Original title |
1,1-Dichloro-1-nitroetan: Dokumentacja proponowanych wartości dopuszczalnych wielkości narażenia zawodowego [in Polish] |
| Bibliographic information |
2005, Vol.43, No.1, p.57-65. 8 ref. |
| Abstract |
1,1-Dichloro-l-nitroethane (DCNE) is a colourless liquid with an unpleasant odour. It is toxic in laboratory animals. Irritation of the eyes, skin, and upper respiratory tract have been observed. DCNE exerts systemic toxic action on parenchymal organs (lung, liver, kidney, heart) and is mutagenic in Salmonella typhimurium. On the basis of the no-observed-adverse-effect-level (NOAEL) for irritation of the upper respiratory tract from animal experiments and the appropriate uncertainty factor, the maximum admissible concentration (TWA) was set at 30 mg/m3. A short-term exposure limit of 60 mg/m3 and irritant (I) notation are recommended. |
| Descriptors (primary) |
toxic effects; toxicology; 1,1-dichloro-1-nitroethane; threshold limit values |
| Descriptors (secondary) |
mutagenic effects; irritants; heart; lung; kidney; Poland; eye irritation; skin allergies; liver |
| Document type |
D - Periodical articles |
| Country / State or Province | Poland |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Genetic factors in reaction to exposures
Occupational exposure limits
|
