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Document ID (ISN)104400
CIS number 05-638
ISSN - Serial title 1232-1087 - International Journal of Occupational Medicine and Environmental Health
Year 2005
Convention or series no.
Author(s) Krakowiak A., Dudek W., Tarkowski M., Świderska-Kiełbik S., Nieścierenko E., Pałczyński C.
Title Occupational asthma caused by cobalt chloride in a diamond polisher after cessation of occupational exposure: A case report
Bibliographic information 2005, Vol.18, No.2, p.151-158. Illus. 19 ref.
Abstract Occupational asthma caused by cobalt chloride was diagnosed in a 35-year-old patient, who worked as a diamond paste polishing disc former. He had been suffering for two years from dyspnoea, cough and symptoms of rhinitis. Skin prick tests (SPTs) with common environmental allergens were found to be negative, while SPTs with cobalt chloride were positive for all applied solutions. Provocation with cobalt chloride caused a significant increase in the proportion of eosinophils, basophils and albumin during the late allergic reaction. Positive lymphocyte transformation caused by cobalt was also observed. It is concluded that cobalt salts may induce occupational asthma; the mechanism may be IgE-mediated.
Descriptors (primary) Poland; cobalt (II) chloride; metalworking industry; abrasive wheels; asthma
Descriptors (secondary) case study; pulmonary function; immunology; sensitization; skin tests; individual susceptibility; allergy tests
Document type D - Periodical articles
Country / State or ProvincePoland
Subject(s) Occupational pathology
Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Inorganic substances
Diseases of the respiratory system (except for pneumoconiosis & similar)
Halogens and their inorganic compounds
Metalworking industry