|Document ID (ISN)||104400|
|ISSN - Serial title
||1232-1087 - International Journal of Occupational Medicine and Environmental Health
|Convention or series no.
||Krakowiak A., Dudek W., Tarkowski M., Świderska-Kiełbik S., Nieścierenko E., Pałczyński C.
||Occupational asthma caused by cobalt chloride in a diamond polisher after cessation of occupational exposure: A case report
||2005, Vol.18, No.2, p.151-158. Illus. 19 ref.
||Occupational asthma caused by cobalt chloride was diagnosed in a 35-year-old patient, who worked as a diamond paste polishing disc former. He had been suffering for two years from dyspnoea, cough and symptoms of rhinitis. Skin prick tests (SPTs) with common environmental allergens were found to be negative, while SPTs with cobalt chloride were positive for all applied solutions. Provocation with cobalt chloride caused a significant increase in the proportion of eosinophils, basophils and albumin during the late allergic reaction. Positive lymphocyte transformation caused by cobalt was also observed. It is concluded that cobalt salts may induce occupational asthma; the mechanism may be IgE-mediated.
||Poland; cobalt (II) chloride; metalworking industry; abrasive wheels; asthma
||case study; pulmonary function; immunology; sensitization; skin tests; individual susceptibility; allergy tests
||D - Periodical articles
|Country / State or Province||Poland|
Toxic and dangerous substances
|Broad subject area(s)
Diseases of the respiratory system (except for pneumoconiosis & similar)
Halogens and their inorganic compounds