| Document ID (ISN) | 104397 |
| CIS number |
05-637 |
| ISSN - Serial title |
0731-3810 - Journal of Toxicology - Clinical Toxicology |
| Year |
2005 |
| Convention or series no. |
|
| Author(s) |
Kubota T., Miyata A. |
| Title |
Acute inhalational exposure to chlorodifluromethane (Freon 22): A report of 43 cases |
| Bibliographic information |
2005, Vol.43, No.4. p.305-308. Illus. 13 ref. |
| Abstract |
43 cases of chlorodifluoromethane (Freon-22) intoxication occurred when a freezer in a seafood factory exploded. In this accident, 80 workers were exposed to Freon-22 gas and 43 workers developed symptoms and were hospitalized. Neurological symptoms including dizziness, headache, and nausea were the most frequently observed (40 of 43 patients). One patient was comatose but recovered within one hour with oxygen inhalation. Airway and respiratory symptoms including dysesthesia of the tongue, pharyngitis, and shortness of breath were also frequently observed (26 of 43 patients). These symptoms disappeared within a few days in all patients. There were no fatalities. Although Freon-22 has been considered to be a chlorofluorocarbon of relatively low toxicity, this incident suggests that potentially significant toxic effects may occur following large exposures. |
| Descriptors (primary) |
toxic effects; Japan; cold storage; food industry; chlorodifluoromethane |
| Descriptors (secondary) |
neurotoxic effects; poisoning; case study; migraine; short-term exposure; functional digestive disorders; unconsciousness; vertigo; symptoms |
| Document type |
D - Periodical articles |
| Country / State or Province | Japan |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Food industry
Halogenated hydrocarbons
Storage and warehousing
|
