|Document ID (ISN)||104371|
|ISSN - Serial title
||1047-322X - Applied Occupational and Environmental Hygiene
|Convention or series no.
||Qu Q., Cohen B.S., Shore R., Chen L.C., Li G., Jin X., Melikian A.A., Yin S., Yan H., Xu B., Li Y., Mu R., Zhang X., Li K.
||Benzene exposure measurement in shoe and glue manufacturing: A study to validate biomarkers
||Dec. 2003, Vol.18, No.12, p.988-998. Illus. 9 ref.
||The aim of this study was to determine whether selected biological markers of exposure to benzene are reliable and sensitive enough to detect low-level exposures. Recruitment of 130 exposed subjects was based on personal exposure measurements collected for three to four weeks prior to collection of biological samples. Personal exposure to benzene was monitored between 1997 and 1998 and results were correlated with the concentrations of two urinary benzene metabolites, trans, trans-muconic acid and S-phenylmercapturic acid. Results indicated that S-phenylmercapturic acid appears to be a good biomarker for detecting and evaluating benzene exposure at concentrations less than 0.25ppm.
||China; benzene; shoe industry; exposure tests; adhesives
||S-phenylmercapturic acid; personal sampling; toluene; xylene; determination in urine; urinary metabolites; dose-response relationship; determination in air; exposure evaluation
||D - Periodical articles
|Country / State or Province||China; USA|
||Toxic and dangerous substances
|Broad subject area(s)
Footwear, leather and fur industry