|Document ID (ISN)||104265|
|ISSN - Serial title
||1231-868X - Podstawy i Metody Oceny Środowiska Pracy
|Convention or series no.
||Dikwatu dibromek [in Polish]|
||2002, Vol.33, No.3, p.51-65. 31 ref.
||Diquat is a non-selective herbicide mainly used in the form of its soluble dibromide salt, commonly also referred to as "diquat". Ingestion of diquat leads to severe lesions of the gastrointestinal tract, kidneys and liver. This intoxication usually leads to death. The exposure to diquat aerosols may lead to irritation of nasal mucosa and upper airways. The acute toxicity of diquat for laboratory animals is relatively high by all routes of administration. Diquat is possibly also mutagenic and foetotoxic, and may exert a negative effect on the development of offspring. No carcinogenic effects have been reported. The recommended maximum exposure limit of 0.1mg/m3 is based on no observed adverse effect levels (NOAEL) and lowest observed adverse effect levels (LOAEL) derived from long-term studies on rats. The proposed short-term exposure limit value of 0.3mg/m3 is based on the irritant effects of the substance.
||Poland; health hazards; toxicology; diquat
||mutagenic effects; embryotoxic effects; herbicides; literature survey; threshold limit values; irritants; criteria document; renal damage; gastrointestinal diseases; permissible levels; animal experiments; determination of exposure limits; agriculture; hepatic damage
||B - Chemical safety information sheets
|Country / State or Province||Poland|
||Toxic and dangerous substances
|Broad subject area(s)
Genetic factors in reaction to exposures