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Document ID (ISN)104188
CIS number 05-373
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2005
Convention or series no.
Author(s) Bleecker M.L., Ford D.P., Lindgren K.N., Hoese V.M., Walsh K.S., Vaughan C.G.
Title Differential effects of lead exposure on components of verbal memory
Bibliographic information Mar. 2005, Vol.62, No.3, p.181-187. Illus. 45 ref.
Abstract To determine if verbal learning and memory retention is affected by lead exposure, the Rey Auditory Verbal Learning Test (RAVLT) was administered to 256 English-speaking lead smelter workers (mean age 41 years and mean employment duration 17 years). Lead exposure variables, based on up to 25 years of prior blood lead data, included a mean current blood lead of 28µg/dl, working lifetime time weighted average blood lead (TWA) of 39µg/dl, and working lifetime integrated blood lead index (IBL) of 728µg-y/dl. Associations of these chronic and recent lead exposure variables with measures from the RAVLT were modelled through multiple linear regressions after controlling for age and educational achievement. It was found that long-term lead exposure interfered with the organisation and recall of previously learned verbal material.
Descriptors (primary) neurotoxic effects; lead; smelting plants; long-term exposure; disturbances of memory
Descriptors (secondary) determination in blood; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Inorganic substances
Lead and compounds
Diseases of the nervous system
Mental health
Smelting and refining operations