| Document ID (ISN) | 104035 |
| CIS number |
05-381 |
| ISSN - Serial title |
1545-9624 - Journal of Occupational and Environmental Hygiene |
| Year |
2004 |
| Convention or series no. |
|
| Author(s) |
Proctor D.M., Panko J.P., Liebig E.W., Paustenbach D.J. |
| Title |
Estimating historical occupational exposure to airborne hexavalent chromium in a chromate production plant: 1940-1972 |
| Bibliographic information |
Nov. 2004, Vol.1, No.11, p.752-767. Illus. 41 ref. |
| Abstract |
The findings of a retrospective exposure assessment for 493 workers who were occupationally exposed to airborne hexavalent chromium (Cr(VI)) at a chromate production plant from 1940 to 1972 are presented. Exposure estimates were based on a job-exposure matrix that related job titles with area monitoring data from 21 industrial hygiene surveys conducted from 1943 to 1971. Former workers were interviewed to determine activity patterns in the plant by job title. This information was combined with Cr(VI) monitoring data to calculate cumulative occupational exposure for each worker. The highest monthly 8-hour average exposures for each worker ranged from 0.003 to 4.1mg/m3. These exposure estimates were combined with mortality data for this cohort to assess the lung cancer risk associated with inhaled Cr(VI). A dose-response relationship was observed for increases in lung cancer mortality with Cr(VI) exposure. |
| Descriptors (primary) |
exposure evaluation; risk factors; chromates; chromium; chromium and compounds |
| Descriptors (secondary) |
mortality; lung cancer; cohort study; determination in air; dose-response relationship; job-exposure relation; long-term study |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Chemicals, plastics and rubber
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Exposure evaluation
Inorganic substances
|
