Document ID (ISN) | 103985 |
CIS number |
05-10 |
Year |
2005 |
Convention or series no. |
ECETOC JACC No.47
|
Title |
1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) CAS No.306-83-2 (Third edition) |
Bibliographic information |
European Centre for Ecotoxicology and Toxicology of Chemicals, Avenue E. Van Nieuwenhuyse 4, Bte. 6, 1160 Bruxelles, Belgium, 13th ed., May 2005. v, 95p. 147ref. |
Abstract |
Conclusions of this criteria document: HCFC-123 has a low toxicity in laboratory animals upon single brief exposure. The liquid is not irritant or sensitizing to the skin, but produces eye irritation. For humans, the most relevant critical effects from brief single exposure are depression of the central nervous system and increased likelihood of cardiac arrhythmia. Repeated exposure may yield liver lesions. |
Descriptors (primary) |
1,1-dichloro-2,2,2-trifluoroethane; toxicology |
Descriptors (secondary) |
neurotoxic effects; literature survey; arrhythmia; criteria document; hepatic damage; ecotoxicology; animal experiments; central nervous system |
Document type |
B - Chemical safety information sheets |
Country / State or Province | Belgium |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
|
Browse category(ies) |
Halogenated hydrocarbons
|