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CISDOC database

Document ID (ISN)103985
CIS number 05-10
Year 2005
Convention or series no. ECETOC JACC No.47
Title 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) CAS No.306-83-2 (Third edition)
Bibliographic information European Centre for Ecotoxicology and Toxicology of Chemicals, Avenue E. Van Nieuwenhuyse 4, Bte. 6, 1160 Bruxelles, Belgium, 13th ed., May 2005. v, 95p. 147ref.
Abstract Conclusions of this criteria document: HCFC-123 has a low toxicity in laboratory animals upon single brief exposure. The liquid is not irritant or sensitizing to the skin, but produces eye irritation. For humans, the most relevant critical effects from brief single exposure are depression of the central nervous system and increased likelihood of cardiac arrhythmia. Repeated exposure may yield liver lesions.
Descriptors (primary) 1,1-dichloro-2,2,2-trifluoroethane; toxicology
Descriptors (secondary) neurotoxic effects; literature survey; arrhythmia; criteria document; hepatic damage; ecotoxicology; animal experiments; central nervous system
Document type B - Chemical safety information sheets
Country / State or ProvinceBelgium
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Halogenated hydrocarbons