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Document ID (ISN)103917
CIS number 05-164
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2003
Convention or series no.
Author(s) Smit L.A.M., van-Wendel-de-Joode B.N., Heederik D., Peiris-John R.J., van der Hoek W.
Title Neurological symptoms among Sri Lankan farmers occupationally exposed to acetylcholinesterase-inhibiting insecticides
Bibliographic information Sep. 2003, Vol.44, No.3, p.254-264. Illus. 32 ref.
Internet access 05-0164.pdf [in English]
Abstract The aim of this study was to evaluate the impact of pesticide use on Sri Lankan farmers' health. 260 rice farmers were surveyed in both low and high pesticide exposure periods. A control group of 55 fishermen was recruited from a nearby fishing community. Acetylcholinesterase activity was measured and data on symptoms were collected by means of questionnaires. 24%of surveyed farmers had suffered at least once from acute pesticide poisoning. Farmers showed significantly more inhibition of cholinesterase activity than controls. Acute symptoms indicative for exposure to cholinesterase-inhibiting pesticides were associated with farming and a higher degree of cholinesterase suppression (more than 13% inhibition). Integrated pest management training resulted in less insecticide use, and less cholinesterase inhibition. Overall reduction in pesticide use seems the best option to protect farmers from the adverse effects of pesticides.
Descriptors (primary) neurotoxic effects; cereal farming; Sri Lanka; agriculture; insecticides; risk factors; rice
Descriptors (secondary) cholinesterase monitoring; pesticide poisoning; acetylcholinesterase; case-control study; limitation of exposure; questionnaire survey; symptoms
Document type D - Periodical articles
Country / State or ProvinceSri Lanka; Netherlands
Subject(s) Agriculture, fishing, animal husbandry
Toxic and dangerous substances
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Diseases of the nervous system
Agricultural chemicals