|Document ID (ISN)||103865|
|ISSN - Serial title
||0340-0131 - International Archives of Occupational and Environmental Health
|Convention or series no.
||Verberk M.M., Brons J.T., SallÚ H.J.A.
||Visual evoked potentials in workers with chronic solvent encephalopathy
||June 2004, Vol.77, No.5, p.328-334. Illus. 26 ref.
||The effectiveness of contrast stimulus to reveal damage to specific visual cortical areas was studied among solvent-exposed workers. 30 male patients aged 48▒9 years with solvent-induced chronic encephalopathy participated in the study, together with 41 controls aged 46▒8 years without solvent exposure. Pattern-reversal checkerboards with low and high contrast were used. At low contrast, the peak-to-peak amplitude in the controls was 57% of the amplitude at high contrast, while among patients, the response at low contrast was only 48% of that at high contrast. Results confirm earlier findings of a physiological basis for the solvent-induced decrease of visual contrast sensitivity. The results also suggest that the neurophysiological examination of the visual system in persons who have undergone exposure to toxic substances might be benefited by the addition of low-contrast stimuli.
||visual function disorders; solvents; encephalopathy
||neurotoxic effects; vision tests; case-control study; male workers
||D - Periodical articles
|Country / State or Province||Netherlands|
Toxic and dangerous substances
|Broad subject area(s)
Occupational medicine, epidemiology
||Diseases of the eye and vision damage
Diseases of the nervous system