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Document ID (ISN)103416
CIS number 04-409
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2004
Convention or series no.
Author(s) Dangman K.H., Storey E., Schenk P., Hodgson M.J.
Title Effects of cigarette smoking on diagnostic tests for work-related hypersensitivity pneumonitis: Data from an outbreak of lung disease in metalworkers
Bibliographic information May 2004, Vol.45, No.5, p.455-467. Illus. 68 ref.
Abstract Following an earlier outbreak of hypersensitivity pneumonitis among a group of metalworkers, a re-examination of data of the 61 patients seen in connection with the outbreak was carried out to explore possible effects of cigarette smoking on the clinical tests used to diagnose hypersensitivity pneumonitis. It is concluded that cigarette smoking can affect the physical examination findings, spirometry and electron spin resonance spectroscopy changes associated with hypersensitivity pneumonitis, making these tests less sensitive and specific, and potentially obscuring the diagnosis. Such changes may contribute to the apparent "protective" effect of smoking on the development of hypersensitivity pneumonitis.
Descriptors (primary) extrinsic allergic alveolitis; smoking; metalworking industry; reliability; diagnosis
Descriptors (secondary) spirometry; interferences; medical examinations; electron spectroscopy
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Metalworking industry
Smoking
Pneumoconioses