| Document ID (ISN) | 103415 |
| CIS number |
04-405 |
| ISSN - Serial title |
0271-3586 - American Journal of Industrial Medicine |
| Year |
2004 |
| Convention or series no. |
|
| Author(s) |
Telišman S., Pizent A., Jurasović J., Cvitković P. |
| Title |
Lead effect on blood pressure of moderately lead-exposed male workers |
| Bibliographic information |
May 2004, Vol.45, No.5, p.446-454. 52 ref. |
| Abstract |
The effect of lead on blood pressure was examined in 100 subjects with moderate-to-low occupational exposure to lead and 51 unexposed controls. Measurements included blood lead (BPb), activity of δ-aminolevulinic acid dehydratase (ALAD), erythrocyte protoporphyrin (EP), blood cadmium (BCd), serum zinc (SZn), serum copper (SCu), haematocrit (Hct), body mass index (BMI) and blood pressure. There was no significant difference in blood pressure between the two groups, possibly because the reference subjects had relatively high BPb levels and significantly higher BMI than the lead workers. Among lead-exposed workers, an increase in systolic blood pressure was significantly associated with increasing EP and BMI. An increase in diastolic blood pressure was significantly associated with increasing BMI and EP and decreasing BCd. It is concluded that a cumulative long-term moderate exposure to lead may result in a significant increase blood pressure. |
| Descriptors (primary) |
male workers; blood pressure; lead |
| Descriptors (secondary) |
protoporphyrin; copper; zinc; ALAD; body weight; statistical evaluation; determination in blood; cadmium; erythrocytes; case-control study |
| Document type |
D - Periodical articles |
| Country / State or Province | Croatia |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Inorganic substances
Cardiovascular diseases
Lead and compounds
|
