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Document ID (ISN)103206
CIS number 04-159
ISSN - Serial title 0340-0131 - International Archives of Occupational and Environmental Health
Year 2004
Convention or series no.
Author(s) Bast-Pettersen R., Ellingsen D.G., Hetland S.M., Thomassen Y.
Title Neuropsychological function in manganese alloy plant workers
Bibliographic information May 2004, Vol.77, No.4, p.277-287. Illus. 54 ref.
Abstract To investigate potential nervous system effects of manganese (Mn) exposure, 100 workers employed in Mn alloy plant workers were compared with 100 age-matched controls. The subjects were examined with a comprehensive neuropsychological test battery. Exposure was assessed by measurement of Mn concentrations in the workroom air, blood and urine. The geometric mean concentration of inhalable Mn in workroom air was 301µg/m3. The concentrations of Mn in blood and urine were higher among the exposed subjects than among the controls. The Mn-exposed subjects had increased postural tremor while conducting a visually guided tremor test compared with the controls. Smoking habits influenced the tremor parameters significantly, the Mn-exposed smokers having more tremor than the non-smoking Mn-exposed subjects. However, no differences between the groups were found in tests for cognitive functions, reaction time or in symptom reporting.
Descriptors (primary) neurotoxic effects; manganese and compounds; alloys; occupational diseases; manganese
Descriptors (secondary) tremor; nervous function tests; cognitive performance; smoking; determination in urine; breathing atmosphere; determination in air; determination in blood; case-control study
Document type D - Periodical articles
Country / State or ProvinceNorway
Subject(s) Metal production and metalworking
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the nervous system
Inorganic substances