Document ID (ISN) | 103206 |
CIS number |
04-159 |
ISSN - Serial title |
0340-0131 - International Archives of Occupational and Environmental Health |
Year |
2004 |
Convention or series no. |
|
Author(s) |
Bast-Pettersen R., Ellingsen D.G., Hetland S.M., Thomassen Y. |
Title |
Neuropsychological function in manganese alloy plant workers |
Bibliographic information |
May 2004, Vol.77, No.4, p.277-287. Illus. 54 ref. |
Abstract |
To investigate potential nervous system effects of manganese (Mn) exposure, 100 workers employed in Mn alloy plant workers were compared with 100 age-matched controls. The subjects were examined with a comprehensive neuropsychological test battery. Exposure was assessed by measurement of Mn concentrations in the workroom air, blood and urine. The geometric mean concentration of inhalable Mn in workroom air was 301µg/m3. The concentrations of Mn in blood and urine were higher among the exposed subjects than among the controls. The Mn-exposed subjects had increased postural tremor while conducting a visually guided tremor test compared with the controls. Smoking habits influenced the tremor parameters significantly, the Mn-exposed smokers having more tremor than the non-smoking Mn-exposed subjects. However, no differences between the groups were found in tests for cognitive functions, reaction time or in symptom reporting. |
Descriptors (primary) |
neurotoxic effects; manganese and compounds; alloys; occupational diseases; manganese |
Descriptors (secondary) |
tremor; nervous function tests; cognitive performance; smoking; determination in urine; breathing atmosphere; determination in air; determination in blood; case-control study |
Document type |
D - Periodical articles |
Country / State or Province | Norway |
Subject(s) |
Metal production and metalworking
|
Broad subject area(s) |
Chemical safety
|
Browse category(ies) |
Diseases of the nervous system Inorganic substances
|