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Document ID (ISN)103038
CIS number 04-30
Year 2004
Convention or series no.
Author(s)
Agency for Toxic Substances and Disease Registry (ATSDR)
Title Toxicological profile for cobalt: Update
Bibliographic information U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry, Division of Toxicology/Toxicology Information Branch, 1600 Clifton Road NE, E-29, Atlanta, GA 30333, USA, Apr. 2004. xxii, 418p. Illus. Approx. 1500 ref.
Internet access http://www.atsdr.cdc.gov/toxprofiles/tp33.pdf [in English]
Abstract This profile characterizes the toxicological and adverse health effects information for cobalt. It was prepared in accordance with guidelines set by the US Agency for Toxic Substances and Disease Registry and the EPA. It identifies and reviews the key literature that describes the toxicological properties of cobalt. Contents: public health statement; relevance to public health; health effects; chemical, physical and radiological information; production, import, export, use and disposal; potential for human exposure; analytical methods; regulations and advisories; glossary. Health hazards from stable (non-radioactive) cobalt include various respiratory disorders (such as asthma, wheezing and pneumonia) among hard metal alloy workers exposed to cobalt dust. In animal experiments, radioactive cobalt shows reproductive and developmental toxicity, cytotoxicity, genotoxicity and carcinogenicity.
Descriptors (primary) cobalt and compounds; cobalt; USA; health hazards; radioactive substances; toxicity evaluation; toxicology
Descriptors (secondary) toxic effects; literature survey; airborne dust; leukaemia; dyspnoea; alloys; criteria document; hard metal pneumoconiosis; limitation of exposure; animal experiments; metalworking industry; legislation; glossary; asthma
Document type B - Chemical safety information sheets
Country / State or ProvinceUSA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Inorganic substances