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Document ID (ISN)102808
CIS number 03-1773
ISSN - Serial title 0003-4878 - Annals of Occupational Hygiene
Year 2002
Convention or series no.
Author(s) Tsai P.J., Shieh H.Y., Lee W.J., Chen H.L., Shih T.S.
Title Urinary 1-hydroxypyrene as a biomarker of internal dose of polycyclic aromatic hydrocarbons in carbon black workers
Bibliographic information Mar. 2002, Vol.46, No.2, p.229-235. 24 ref.
Abstract In this study, a total of 30 workers exposed to carbon black were selected, including eight wet pelletizing workers and 22 packaging workers. For all selected workers, urine samples were collected on the first day pre-shift, first day post-shift and fifth day post-shift, and their urinary 1-hydroxypyrene levels (1-OHP) were determined (denoted as BM1pre, BM1post and BM5post, respectively). Personal respiratory exposures, including both inhalable particle-bound PAHs (Cipb) and gaseous PAHs (Cgas), together with dermal exposure to particle-bound PAHs (Cskin) were measured. Personal background information, including age, sex and smoking habit, was registered. Pyrene exposure was statistically significantly correlated with exposure to PAHs and carcinogenic PAHs. The resultant regression coefficients for sex, smoking habit and age were statistically insignificant. In conclusion, this study suggests BM5post could be a suitable indicator for PAH exposures of carbon black workers, on the condition that both respiratory and dermal exposures are assessed.
Descriptors (primary) chemical industry; aromatic hydrocarbons; exposure tests; polycyclic hydrocarbons; 1-hydroxypyrene; carbon black
Descriptors (secondary) Taiwan (China); pyrene; determination in urine; exposure evaluation; absorbed dose; skin absorption
Document type D - Periodical articles
Country / State or ProvinceTaiwan (China)
Subject(s) Chemicals, plastics and rubber
Broad subject area(s) Chemical safety
Browse category(ies) Biological monitoring
Chemical industry
Polycyclic hydrocarbons
Aromatic hydrocarbons
Alcohols