|Document ID (ISN)||102776|
|ISSN - Serial title
||1076-2752 - Journal of Occupational and Environmental Medicine
|Convention or series no.
||Yu I.T.S., Lee N.L., Zhang X.H., Chen W.Q., Lam Y.T., Wong T.W.
||Occupational exposure to mixtures of organic solvents increases the risk of neurological symptoms among printing workers in Hong Kong
||Apr. 2004, Vol.46, No.4, p.323-330. 29 ref.
||The health effects of low-dose occupational exposure to organic solvents remains unclear. A cross-sectional survey was conducted among 762 male printing workers to assess the effects of exposure to mixtures of n-hexane, toluene, isopropyl alcohol and benzene on neurological and other symptoms. After adjusting for age, smoking, alcohol consumption, past exposure history, working hours and shift work, it was found that exposure to solvent mixtures was significantly associated with the total number of neurological symptoms and with the prevalence of specific symptoms of the nervous system and mucous membrane irritation. The adjusted odds ratio of neurovegetative lability (1.7-5.9), abnormal or reduced smell (1.6-4.1), memory loss (1.8) and mucous membrane irritation symptoms (1.5-4.6) significantly increased in the exposed group, especially when the summation index of exposure exceeded unity.
||neurotoxic effects; Hong Kong; risk factors; mixtures; organic solvents; printing industry
||hexane; benzene; toluene; isopropyl alcohol; irritation; cross-sectional study; neurovegetative disorders; loss of smell; hazard evaluation; mucous membranes; disturbances of memory
||D - Periodical articles
|Country / State or Province||Hong Kong|
||Paper-making and printing
|Broad subject area(s)
||Occupational medicine, epidemiology
||Printing, photography and photocopying industry
Diseases of the nervous system