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Document ID (ISN)102518
CIS number 03-1762
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2003
Convention or series no.
Author(s) Farahat T.M., Abdelrasoul G.M., Amr M.M., Shebl M.M., Farahat F.M., Anger W.K.
Title Neurobehavioural effects among workers occupationally exposed to organophosphorous pesticides
Bibliographic information Apr. 2003, Vol.60, No.4, p.279-286. Illus. 43 ref.
Abstract In this study, 52 occupationally-exposed male workers involved in applying organophosphorus pesticides to cotton crops were compared with 50 unexposed male controls matched by age, socioeconomic class and years of education. Participants completed a questionnaire on personal, occupational and medical factors. They were subjected to general and neurological clinical examinations, neurobehavioural tests and serological analyses for acetylcholinesterase. After correcting for age and education, the exposed participants exhibited significantly lower performance than controls on six neurobehavioural tests. Longer years of work with pesticides were associated with lower performance on most neurobehavioural tests after adjusting for multiple comparisons. Although serum acetylcholinesterase was significantly lower in the exposed participants, it was not significantly correlated with either neurobehavioural performance or neurological abnormalities.
Descriptors (primary) neurotoxic effects; cotton farming; sensory aptitude; pesticides; organophosphorus compounds
Descriptors (secondary) nervous function tests; acetylcholinesterase; Egypt; medical examinations; case-control study; length of exposure; determination in blood; questionnaire survey
Document type D - Periodical articles
Country / State or ProvinceEgypt; USA
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the nervous system
Agricultural chemicals