| Document ID (ISN) | 102279 |
| CIS number |
03-1091 |
| ISBN(s) |
92-4-153050-2 |
| Year |
2003 |
| Convention or series no. |
CICAD No.50
|
| Author(s) |
Fisher J.F.
Inter-Organization Programme for the Sound Management of Chemicals (IOMC) |
| Title |
Elemental mercury and inorganic mercury compounds: Human health aspects |
| Bibliographic information |
World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 2003. iv, 61p. 298 ref. |
| Internet access |
http://www.who.int/ipcs/publications/cicad/en/cicad50.pdf [in English]
|
| Abstract |
Conclusions of this criteria document: mild subclinical signs of central nervous toxicity can be observed among workers exposed to elemental mercury at a concentration of 20µg/m3 or above for several years. Neurological and behavioural disorders have been observed following inhalation of elemental mercury vapour or dermal application of inorganic mercury-containing medicinal products. The primary effect of long-term oral exposure to low amounts of inorganic mercury compounds is renal damage; immunological effects have also been shown. Data from animal studies indicate that mercuric chloride has some carcinogenic activity in male rats; parenteral administration of inorganic mercury compounds is embryotoxic and teratogenic in rodents. Inorganic mercury compounds seem to interact with and damage DNA in vitro. |
| Descriptors (primary) |
IPCS; health hazards; toxicology; mercury and compounds |
| Descriptors (secondary) |
toxic effects; criteria document; literature survey; ILO; UNEP; WHO; mercuric chloride; mercury chloride; mercury; mercuric acetate; renal damage; ecotoxicology; animal experiments; lethal concentration 50; mercury sulfide; neurotoxic effects |
| Document type |
B - Chemical safety information sheets |
| Country / State or Province | USA; WHO |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Mercury and compounds
Inorganic substances
|
