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Document ID (ISN)101985
CIS number 03-746
ISSN - Serial title 0003-4878 - Annals of Occupational Hygiene
Year 2001
Convention or series no.
Author(s) Symanski E., Chan W., Chang C.C.
Title Mixed-effects models for the evaluation of long-term trends in exposure levels with an example from the nickel industry
Bibliographic information Jan. 2001, Vol.45, No.1, p.71-81. Illus. 45 ref.
Abstract The purpose of this paper is to examine certain features of data from long-term studies and to present a general conceptual framework by which these features may be taken into account so that statistically valid inferences can be made. Statistical methods that rely on the application of mixed-effects models are proposed for evaluating long-term trends in exposure to workplace contaminants. The mixed-effects model presented herein has fixed effects for trend components and random effects for workers, job groups, buildings and manufacturing plants. It provides information about the magnitude of sources of variation associated with different groupings of workers. The mixed-effects model was applied to a large database of shift-long personal exposure measurements collected on workers exposed to nickel aerosols in the nickel-producing industry.
Descriptors (primary) aerosols; long-term study; smelting plants; mathematical models; contamination
Descriptors (secondary) nickel; buildings; statistical evaluation; exposure evaluation; premises
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Smelting and refining operations