| Document ID (ISN) | 101707 |
| CIS number |
03-760 |
| ISSN - Serial title |
0271-3586 - American Journal of Industrial Medicine |
| Year |
2003 |
| Convention or series no. |
|
| Author(s) |
Clary T., Ritz B. |
| Title |
Pancreatic cancer mortality and organochlorine pesticide exposure in California, 1989-1996 |
| Bibliographic information |
Mar. 2003, Vol.43, No.3, p.306-313. Illus. 29 ref. |
| Abstract |
Earlier studies have suggested a possible link between organochlorine pesticides and the occurrence of pancreatic cancers. California maintains a death file and a pesticide reporting system that allows examination of this relationship in residents of high-use areas. Mortality odds ratios were used to compare deaths from pancreatic cancer from 1989 to 1996 with a random sample of non-cancer deaths. Using pesticide data for three agricultural counties, 102 postal codes were classified for pesticide usage from 1972 to 1989. The effect of pesticide applications were estimated by logistic regression for each postal code after controlling for possible confounders. Among long-term residents, pancreatic cancer mortality was elevated for those living in postal codes with the highest use of 1,3-dichloropropene, captafol, pentachloronitrobenzene and dieldrin. No dose-response relationship was observed. |
| Descriptors (primary) |
California; dichloropropene; chlorinated organic compounds; risk factors; pesticides; tumour of the pancreas; cancer; mortality |
| Descriptors (secondary) |
USA; dieldrin; quintozene; frequency rates; exposure evaluation; statistical evaluation; captafol |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Agricultural chemicals
Endocrine diseases
Halogenated hydrocarbons
|
