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CISDOC database

Document ID (ISN)101518
CIS number 03-754
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2003
Convention or series no.
Author(s) Page E.H., Cook C.K., Hater M.A., Mueller C.A., Grote A.A., Mortimer V.D.
Title Visual and ocular changes associated with exposure to two tertiary amines
Bibliographic information Jan. 2003, Vol.60, No.1, p.69-75. Illus. 11 ref.
Abstract To determine if exposure to dimethylisopropanolamine (DMIPA) and dimethylaminoethanol (DMAE) in a label-printing plant was associated with visual disturbances or ocular changes, questionnaire surveys, eye examinations (visual acuity, contrast sensitivity, slit lamp biomicroscopy and pachymetry) and measurements of workplace airborne concentrations of DMIPA and DMAE were performed over a two-week period. 89% of line (high-speed printing) workers reported having experienced blurry vision while at work in the past 12 months, compared to 12.5% of prime (lower-speed printing) workers. The mean time weighted average concentrations of DMIPA, DMAE and total amines were significantly higher in the line division than in the prime division. Higher levels of total amines were associated with increased risk of reporting blurry vision, halo vision, and blue-gray vision. The prevalence of corneal opacity increased with increasing duration of exposure to total amines and with increasing concentration of total amines. There was a statistically significant relation between total amine concentration and increased risk of reduced bilateral visual acuity and 2.5% contrast sensitivity.
Descriptors (primary) visual function disorders; printing industry; risk factors; printing inks; aliphatic amines
Descriptors (secondary) eye examinations; lens and cornea opacities; dimethylaminoethanol; exposure evaluation; vision tests; amblyopia
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the eye and vision damage
Aliphatic amines
Printing, photography and photocopying industry