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Document ID (ISN)101268
CIS number 03-279
ISSN - Serial title 0340-0131 - International Archives of Occupational and Environmental Health
Year 2002
Convention or series no.
Author(s) Wang V.S., Lee M.T., Chiou J.Y., Guu C.F., Wu C.C., Wu T.N., Lai J.S.
Title Relationship between blood lead levels and renal function in lead battery workers
Bibliographic information Oct. 2002, Vol.75, No.8, p.569-575. 40 ref.
Abstract The aim of this study was to investigate the correlation between blood lead (PbB) levels and renal function indices of blood-urea nitrogen (BUN), serum creatinine (SC) and uric acid (UA) among lead battery industry workers with exposure to lead. 229 workers of both genders from two lead battery factories were recruited in this cross-sectional study. Personal airborne and blood samples were collected on the same day. A positive correlation between PbB levels and individual renal function index of BUN, SC, and UA was found. PbB levels and renal function indices showed significant difference between male and female workers. An increment of 10µg/dL PbB produced an increase of 0.62mg/dL BUN and an increase of 0.085mg/dL UA. For all workers, there was a significant dose-response relationship between PbB and BUN and UA levels. It is suggested that blood-urea nitrogen and uric acid be considered as indicators of renal dysfunction in lead-exposed workers.
Descriptors (primary) renal dysfunction; exposure tests; battery and dry cell manufacture; lead
Descriptors (secondary) creatinine; uric acid; urea; exposure evaluation; determination in blood; renal function tests; sex-linked differences; dose-response relationship; determination in air; cross-sectional study
Document type D - Periodical articles
Country / State or ProvinceTaiwan (China)
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the kidney and the urinary system
Biological monitoring
Manufacturing of electrical appliances and equipment
Lead and compounds
Inorganic substances