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Document ID (ISN)101134
CIS number 03-434
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2000
Convention or series no.
Author(s) Russi M., Buitrago M., Goulet J., Calello D., Perlotto J., van Rhijn D., Nash E., Friedland G., Hierholzer W.
Title Antiretroviral prophylaxis of health care workers at two urban medical centers
Bibliographic information Nov. 2000, Vol.42, No.11, p.1092-1100. 33 ref.
Abstract This study examined the influence of job category, source patient HIV status and exposure type on whether health care workers initiated antiretroviral prophylaxis after potential blood-borne pathogen exposures. Of 639 exposures over an 18-month period, 82 individuals (13%) elected to receive prophylaxis, of whom 66% took medications for fewer than 96 hours and only 12% completed a 4-week course. Reasons for early drug discontinuation included confirmation of source patient HIV negative serological status (65%), gastrointestinal side effects (13%), headache (4%), and personal decision after counseling or other inputs (18%). Individuals exposed to HIV-positive source patients were more likely to initiate prophylaxis (odds ratio (OR), 5.1). Licensed nurses were less likely than others to accept prophylaxis (OR 0.5), whereas physicians and medical students were more likely to accept prophylaxis (OR 1.9).
Descriptors (primary) occupational accidents; contagion; immunodeficiency syndrome; prophylaxis; hospitals; health care personnel; infection control
Descriptors (secondary) infectious diseases; medical treatment; psychology of medical prevention
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Commerce, services, offices
Broad subject area(s) Biological hazards
Browse category(ies) HIV/AIDS
Health care services
Bacterial and parasitic diseases