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Document ID (ISN)101052
CIS number 03-275
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2000
Convention or series no.
Author(s) Dor F., Haguenoer J.M., Zmirou D., Empereur-Bissonnet P., Jongeneelen F.J., Nedellec V., Person A., Ferguson C.C., Dab W.
Title Urinary 1-hydroxypyrene as a biomarker of polycyclic aromatic hydrocarbons exposure of workers on a contaminated site: Influence of exposure conditions
Bibliographic information Apr. 2000, Vol.42, No.4, p.391-397. Illus. 41 ref.
Abstract The aim of the study was to determine the exposure levels of workers to polycyclic aromatic hydrocarbons on gasworks sites through the measurement of urinary 1-hydroxypyrene. Start-of-shift and end-of-shift urine samples were collected during five consecutive days, once in November and a second time in June. Four groups of workers were selected according to their activity. Increased exposure was only found among workers involved in the remediation of a site, with levels of 0.16 to 2.31Ámol/mol creatinine, while the median level among the nonsmoker referent group was 0.02Ámol/mol creatinine. Smokers had greater exposure levels than non-smokers in every group. It is concluded that this method allows the assessment of exposure of persons on contaminated soil on the condition that the exposed subjects be in direct contact with the soil.
Descriptors (primary) aromatic hydrocarbons; polycyclic hydrocarbons; exposure tests; gas industry; 1-hydroxypyrene
Descriptors (secondary) creatinine; smoking; determination in urine; environmental pollution; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceFrance; United Kingdom; Netherlands
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Power generation and distribution
Biological monitoring
Polycyclic hydrocarbons
Aromatic hydrocarbons