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CISDOC database

Document ID (ISN)100173
CIS number 02-1323
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2000
Convention or series no.
Author(s) Semple S., Dick F., Osborne A., Cherrie J.W., Soutar A., Seaton A., Haites N.
Title Impairment of colour vision in workers exposed to organic solvents
Bibliographic information Sep. 2000, Vol.57, No.9, p.582-587. Illus. 31 ref.
Abstract Since exposure to mixed solvents is associated with impairment of colour vision, a study was conducted on 68 male dockyard workers and 42 controls. Indices of exposure to solvents were calculated for all subjects. Colour vision was tested and, in order to assess the possibility of genetic effects, genotypes of glutathione S-transferase M1 and T1 and N-acetyltransferase 2 polymorphisms were determined. Increasing annual exposure to solvents was associated with reduced colour vision, but no significant association was found between such acquired impairment and genetic polymorphisms.
Descriptors (primary) colour vision deficiency; genetic effects; colour vision; organic solvents
Descriptors (secondary) dock work; exposure evaluation; glutathione transferase; transferases
Document type D - Periodical articles
Country / State or ProvinceUnited Kingdom
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Diseases of the eye and vision damage