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Document ID (ISN)100018
CIS number 02-1351
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2001
Convention or series no.
Author(s) Wang X.R., Yano E., Wang M., Wang Z., Christiani D.C.
Title Pulmonary function in long-term asbestos workers in China
Bibliographic information July 2001, Vol.43, No.7, p.623-629. 30 ref.
Abstract The aim of this study was to provide further understanding of the radiographic physiological associations in nonsmoking and smoking asbestos workers. Radiographic asbestosis, pleural lesion, and pulmonary function were studied in 269 Chinese asbestos workers, with average exposure periods of 23yrs for male workers and 18yrs for female workers. Their functional data were compared with those of 274 controls without exposure to dust. Although most of the male workers were smokers, none of the female workers smoked. In comparison with controls, asbestos workers had significantly lower lung volume and diffusing capacity, irrespective of sex. Female workers and smoking male workers had lower measurements of one-second forced expiratory volume and instantaneous forced expiratory flow at 50% and 25% of forced vital capacity. After adjustment for relevant covariates, asbestos exposure, asbestosis, and pleural abnormalities were associated with decreased parameters of pulmonary function, including lung volume, diffusing capacity and airway flow.
Descriptors (primary) asbestos; long-term exposure; pulmonary function; asbestosis
Descriptors (secondary) China; pleural thickening; chrysotile; smoking; occupation disease relation; radiographic interpretation; confounding factors; respiratory function tests; sex-linked differences; job-exposure relation; case-control study
Document type D - Periodical articles
Country / State or ProvinceChina; Japan; USA
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Pneumoconioses
Asbestos